5.2 Acute Toxicity: OECD Guidelines 423 and 425
5.2 Acute Toxicity: OECD Guidelines 423 and 425 contains 2 topic pages in Phase 5 — Toxicology Studies (Acute, Sub-Acute, Sub-Chronic, Chronic).
Topic Group
Topics
Continue through the related topic pages.
5.2.1 OECD Test Guideline 423 — Acute Toxic Class Method (ATM)
The Acute Toxic Class Method evaluates acute lethality using sequential dosing of small groups of three animals at fixed, internationally standardised dose...
5.2.2 OECD Test Guideline 425 — Up-and-Down Procedure (UDP)
The Up-and-Down Procedure dispenses with fixed group dosing in favour of sequential dosing of individual animals, with each subsequent animal's dose...