3.7 High-Throughput Screening (HTS)
3.7 High-Throughput Screening (HTS) contains 2 topic pages in Phase 3 — In-Vitro Pharmacological Screening.
Topic Group
Topics
Continue through the related topic pages.
3.7.1 Assay Quality Metrics in HTS
The statistical robustness of an HTS assay is conventionally quantified using the Z-factor, a dimensionless parameter that incorporates both the separation...
3.7.2 From Primary Hit to Confirmed Hit
Compounds showing activity in a single-concentration primary HTS campaign ('primary hits') are not immediately considered validated actives; they are...